Proteomics of Biological Systems: Protein Phosphorylation Using Mass Spectrometry Techniques pdf epub fb2

Proteomics of Biological Systems: Protein Phosphorylation Using Mass Spectrometry Techniques by Bryan M. Ham epub fb2 djvu

Author: Bryan M. Ham
Title: Proteomics of Biological Systems: Protein Phosphorylation Using Mass Spectrometry Techniques
ISBN: 1118028961
ISBN13: 978-1118028964
Other Formats: doc mobi azw lit
Pages: 376 pages
Publisher: Wiley; 1 edition (November 15, 2011)
Language: English
Size EPUB version: 1410 kb
Size FB2 version: 1632 kb
Category: Science & Math
Subcategory: Biological Sciences

Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies.

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